Fabrication of Alginate based nanofiber Wound Dressing
Human health is a very important and complex issue that mankind has always paid attention to in all eras. The use of medicine during illness, wound repair, tissue repair, etc. has been used since ancient times. Nature itself is a vast and extraordinary source of medicinal and therapeutic substances that need to be carefully identified. Lands and seas each have a huge range of creatures, many of which are still unknown. The sea and marine creatures, including fish, crustaceans, vegetation, etc., are valuable ecosystems rich in food, medicine, and many unknown uses. At this point, you can find a work area and try to get a job opportunity. The most specific and prominent substance that can be extracted from algae is alginate. Molecular alginate is non-toxic, biocompatible and natural. It is a polysaccharide substance that is usually extracted from brown seaweed. Alginate dressing causes faster wound healing due to its ability to carry medicine. In order to perform better and carry more medicine by the dressing, it is better to use nanofibers in its preparation.
Description of the innovation of the plan:
Although the production of alginate dressing alone will protect the wound and promote wound healing, the use of drugs that stimulate wound healing will accelerate the healing process. Therefore, after achieving the technique of producing suitable alginate nanofibers, in the next step, we will use the drug dexpanthenol in order to stimulate the wound healing factors caused by burns by combining it with alginate polymer solution before electrospinning inside the nanofibers. By reviewing past works, this drug has not been used in addition to the aforementioned polymer composition, and the majority of past research have been investigating antibacterial drugs with the aim of disinfecting wounds without drugs that stimulate wound healing factors. Dexpanthenol drug is a type of stable alcoholic compound with suitable skin penetration, which stimulates wound healing factors by causing minimal skin sensitivity, which means that by using this drug, a suitable environment for the proliferation of fibroblasts and collagen, as well as reducing inflammation at the wound site, is created. It turns out that it accelerates the healing process of the wound, and in this case, treatment costs are reduced.